MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature Sensitive Mutants via Molecular Inversion Probes
Calvin A. Mok, Vinci Au, Owen A. Thompson, Mark L. Edgley, Louis Gevirtzman, John Yochem, Josh Lowry, Nadin Memar, Matthew R. Wallenfang, Dominique Rasoloson, Bruce A. Bowerman, Ralf Schnabel, Géraldine Seydoux, Donald G. Moerman, R Waterston
The paper introduces MIP-MAP, a method to map temperature-sensitive mutations in C. elegans using molecular inversion probes, achieving high-resolution genetic mapping with high-throughput sequencing.
Genetics · Aug 21, 2017Peer-reviewedGenomics