Author

Jon R. Armstrong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Amitabh C. PandeyiD· 1 shared Ankur SharmaiD· 1 shared Austin CrinklawiD· 1 shared Azeem Siddique· 1 shared Bicheng Yang· 1 shared Costerwell KhyriemiD· 1 shared Dante DeAscanisiD· 1 shared Eric J. TopoliD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Amitabh C. PandeyORCID

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2 papers

Recent·Most cited

A CRISPR/Cas9-based enhancement of high-throughput single-cell transcriptomics

Amitabh C. Pandey, Jon Bezney, Dante DeAscanis, Ethan Kirsch, Farin Ahmed, Austin Crinklaw, Kumari Sonal Choudhary, Tony Mandala, Jeffrey Deason, Jasmin Hamidi, Azeem Siddique, Sridhar Ranganathan, Keith Brown, Jon R. Armstrong, Steven Robert Head, , Eric J. Topol

The paper introduces scCLEAN, a CRISPR/Cas9-based method to enhance single-cell transcriptomics by improving library complexity and isoform detection.

Nature Communications · May 19, 2025Peer-reviewedGenetics

STOmics-GenX: CRISPR based approach to improve cell identity specific gene detection from spatially resolved transcriptomics

Jennifer Currenti, Liang Qiao, Rhea Pai, Saurabh Gupta, Costerwell Khyriem, Kellie Wise, Xiaohuan Sun, Jon R. Armstrong, Jordan Crane, Smita Pathak, Bicheng Yang, Jacob George, Jasmine Plummer, Luciano Gastón Martelotto, Ankur Sharma

STOmics-GenX improves gene detection in spatial transcriptomics by integrating CRISPRclean with Stereo-seq, enhancing cell type annotation and biomarker identification in hepatocellular carcinoma.

bioRxiv · Dec 8, 2022 · PreprintMolecular Biology