Clusterin reverses epitheliopathy, reduces inflammation, and restores goblet cells and corneal nerves in a mouse model of autoimmune dry eye
Jonas Franz, Tat Fong Ng, Shivali Gupta, Mark R. Wilson, M. Elizabeth Fini, Sharmila Masli
This study tests clusterin's therapeutic effects in a mouse model of autoimmune dry eye, finding it improves corneal barrier function, nerve density, and goblet cell regeneration while reducing inflammation, comparable to dexamethasone.
Scientific Reports · Feb 15, 2026Peer-reviewedImmunology