Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis
Jonathan Delhermite, Lionel Tafforeau, Sunny Sharma, Virginie Marchand, Ludivine Wacheul, Ruben Lattuca, Simon Desiderio, Yuri Motorin, Eric Bellefroid, Denis L. J. Lafontaine
This study investigates the role of fibrillarin in ribosome biogenesis and its impact on neural crest cell development in Xenopus laevis, revealing developmental defects and hypomethylation patterns in rRNA.
PLoS Genetics · Jan 18, 2022Peer-reviewedDevelopmental Biology