This study identifies cFos as a pro-viral factor for Influenza A virus, showing it enhances cell survival and reduces interferon-β expression to facilitate viral replication.

Journal of General Virology · Jan 14, 2026Peer-reviewedMicrobiology

Identification and characterization of interactions between Influenza A Virus NS1 protein and the human ubiquitin proteasome system

Laurie-Anne Lamotte, Samuel Kindylides, Chloé Gaupin, Caroline Demeret, Lionel Tafforeau

This study identifies 98 UPS factors interacting with IAV NS1 proteins and functionally characterizes 18 of them to understand their role in viral immune evasion.

bioRxiv · Oct 5, 2023 · PreprintMolecular Biology

Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis

Jonathan Delhermite, Lionel Tafforeau, Sunny Sharma, Virginie Marchand, Ludivine Wacheul, Ruben Lattuca, Simon Desiderio, Yuri Motorin, Eric Bellefroid, Denis L. J. Lafontaine

This study investigates the role of fibrillarin in ribosome biogenesis and its impact on neural crest cell development in Xenopus laevis, revealing developmental defects and hypomethylation patterns in rRNA.

PLoS Genetics · Jan 18, 2022Peer-reviewedDevelopmental Biology