Author

Jonathan I. Wilde

GlaxoSmithKline (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Claire CrafteriD· 1 shared Courtney M. SchroederiD· 1 shared Darerca OweniD· 1 shared Helen R. MottiD· 1 shared Jessica CorryiD· 1 shared Jose J. Vicenté-Garcia· 1 shared Kadalmani Krishnan· 1 shared Michael J.O. WakelamiD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Claire CrafterORCID

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1 paper

Recent·Most cited

Assembly of novel, nuclear dimers of the PI3-Kinase regulatory subunits underpins the pro-proliferative activity of the Cdc42-activated tyrosine kinase, ACK

Natasha S. Clayton, Millie Fox, Jose J. Vicenté-Garcia, Courtney M. Schroeder, Trevor D. Littlewood, Jonathan I. Wilde, Jessica Corry, Kadalmani Krishnan, Qifeng Zhang, Michael J.O. Wakelam, Murray J. B. Brown, Claire Crafter, Helen R. Mott, Darerca Owen

The paper shows ACK promotes cell proliferation by stabilizing p85 regulatory subunits and forming nuclear dimers, which may contribute to oncogenesis through novel PI3-Kinase regulation.

bioRxiv · Oct 4, 2019 · PreprintMolecular Biology