Author

Murray J. B. Brown

GlaxoSmithKline (United Kingdom)ORCID 0000-0002-2393-7686Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Claire CrafteriD· 1 shared Courtney M. SchroederiD· 1 shared Darerca OweniD· 1 shared Helen R. MottiD· 1 shared Jessica CorryiD· 1 shared Jonathan I. Wilde· 1 shared Jose J. Vicenté-Garcia· 1 shared Kadalmani Krishnan· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Claire CrafterORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintOct 4, 2019

Assembly of novel, nuclear dimers of the PI3-Kinase regulatory subunits underpins the pro-proliferative activity of the Cdc42-activated tyrosine kinase, ACK

Natasha S. Clayton, Millie Fox, Jose J. Vicenté-Garcia…·Darerca Owen

The paper shows ACK promotes cell proliferation by stabilizing p85 regulatory subunits and forming nuclear dimers, which may contribute to oncogenesis through novel PI3-Kinase regulation.

3 citations

humanexperimental assay

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