Author

Jonathan M. G. Chamberlain

Immunocore (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Abdullah Aljohani· 1 shared Alexandra Chapman· 1 shared Alice Hayward-Wills· 1 shared Amal Alsubaiti· 1 shared Christoph WülfingiD· 1 shared Christopher J. Holland· 1 shared Gwilym Phillips· 1 shared Lan Huynh· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Abdullah Aljohani

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1 paper

Recent·Most cited

ImmTACs overcome cytotoxic T cell suppression

Lan Huynh, Abdullah Aljohani, Amal Alsubaiti, Tressan Grant, Alexandra Chapman, Gwilym Phillips, Jonathan M. G. Chamberlain, Alice Hayward-Wills, Ute Jungwirth, Mariolina Salio, Christopher J. Holland, Christoph Wülfing

This study investigates how ImmTACs activate suppressed cytotoxic T cells, finding they can induce cytolysis but not IFN-gamma secretion, and enhance CTL polarization and calcium signaling.

Immunotherapy Advances · Dec 31, 2025Peer-reviewedImmunology