Author
Immunocore (United Kingdom)ORCID 0000-0002-4821-3801Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Natasha Fisher-Pearson, Martin Joseph Lett, Isaac W. D. Maylam…·Jethro S. Johnson
The paper shows that gut archaea produce 5-OP-RU, which activates MAIT cells, linking archaea to human immunity.
Lan Huynh, Abdullah Aljohani, Amal Alsubaiti…·Christoph Wülfing
This study investigates how ImmTACs activate suppressed cytotoxic T cells, finding they can induce cytolysis but not IFN-gamma secretion, and enhance CTL polarization and calcium signaling.
Daniel J. Burns, Alex Look, Steven Turner…·Salah Mansour
This study determines the crystal structures of human and macaque CD1d bound to -GalCer, revealing conserved ligand-responsive conformational flexibility at Phe84 that modulates antigen presentation.