Spatial analysis of IPMNs defines a paradoxical KRT17-positive, low-grade epithelial population harboring malignant features
Jay Li, Georgina Branch, Justin Macchia, Ahmed M. Elhossiny, Nandini Arya, Julia Liang, Padma Kadiyala, Nicole Peterson, Richard S. Kwon, Jorge D. Machicado, Erik‐Jan Wamsteker, Allison R. Schulman, George Philips, Stacy B. Menees, Jonathan Xia, , Eileen S. Carpenter
The paper identifies a KRT17-positive, low-grade epithelial population in IPMNs with malignant features using spatial transcriptomics and single-cell RNA sequencing.
Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2026Peer-reviewedCancer Biology