Molecular BiologybioRxivPreprint
Prolonged HPA axis dysregulation in postpartum depression associated with adverse lifeexperiences during development: a cross-species translational study for a novel therapeutic approach
Minae Niwa, Sedona Lockhart, Daniel J. Wood…·Akira Sawa
This study shows that adolescent stress leads to prolonged HPA axis dysregulation and postpartum depression, with a GR antagonist showing therapeutic potential in mice and humans.