YX0798 Is a Highly Potent, Selective, and Orally Effective CDK9 Inhibitor for Treating Aggressive Lymphoma
Changying Jiang, Yu Xue, Hong Kim, Qingsong Cai, Tianci Zhang, Lei Nie, Joseph Mitchell McIntosh, Yang Liu, Haiying Chen, Jia Zhou, Michael L. Wang
This paper identifies YX0798 as a potent, selective, and orally effective CDK9 inhibitor that overcomes therapeutic resistance in lymphoma by inducing transcription reprogramming and cell death.
Blood Advances · Jul 21, 2025Peer-reviewedCancer Biology