Author

Joshua R. Squires

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Andrew Daniel HoffmanniD· 1 shared Carolina ReduzziiD· 1 shared Clive Henry WasserfalliD· 1 shared David ScholteniD· 1 shared Deyu FangiD· 1 shared Elizabeth Hyun· 1 shared Fangjia Tong· 1 shared Hannah Faisal AlmubarakiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrew Daniel HoffmannORCID

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1 paper

Recent·Most cited

Rare Subset of T Cells Form Heterotypic Clusters with Circulating Tumor Cells to Foster Cancer Metastasis

David Scholten, Lamiaa El-Shennawy, Yuzhi Jia, Youbin Zhang, Elizabeth Hyun, Carolina Reduzzi, Andrew Daniel Hoffmann, Hannah Faisal Almubarak, Fangjia Tong, Nurmaa Khund Dashzeveg, Yuanfei Sun, Joshua R. Squires, Janice Lu, Leonidas C. Platanias, Clive Henry Wasserfall, , Huiping Liu

The paper identifies a rare subset of CD4 and CD8 double positive T cells that form clusters with circulating tumor cells, promoting cancer metastasis through immune suppression and integrin-mediated interactions.

bioRxiv · Apr 1, 2025 · PreprintCancer Biology