Author

Juan Guo

Dalian University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:plant (other)· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Research Focus:synaptic & neural circuits· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Chengyun ZhangiD· 1 shared Chongyang LiiD· 1 shared Guanghong CuiiD· 1 shared Hanjie Yang· 1 shared Hongli HouiD· 1 shared Hongliang DuaniD· 1 shared Jens NielseniD· 1 shared Jian Wang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Chengyun ZhangORCID

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2 papers

Recent·Most cited

HighFold-Lasso: Topology-Guided Prediction of Lasso Peptide Structures Using AlphaFold3

Sen Cao, Chengyun Zhang, Hanjie Yang, Yutong Ge, Hongli Hou, Zhu Ning, Yaling Wu, Jisong Mo, Juan Guo, Chongyang Li, JINGJING GUO, Hongliang Duan

HighFold-Lasso predicts lasso peptide structures using topology-guided methods, achieving perfect topology success and low RMSD on a test set of 52 structures.

bioRxiv · Oct 16, 2026 · PreprintBioinformatics

Biosynthesis of bisbenzylisoquinoline alkaloids

Qishuang Li, Xinyi Li, Xiang Jiao, Guanghong Cui, Xiangmei Tan, Ying Ma, Yuxing Wang, Yaqiu Zhao, Jian Wang, Wenbo Xu, Tong Chen, Yating Hu, Ping Su, Yifeng Zhang, Jens Nielsen, , Luqi Huang

This study identifies the enzymatic pathway for bisbenzylisoquinoline alkaloid biosynthesis and reveals a non-canonical redox-mediated mechanism for stereochemical control.

bioRxiv · May 26, 2026 · PreprintBiochemistry