Author

Julia Newton-Bishop

Great Ormond Street Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:fine-mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Jérémie NsengimanaiD· 3 shared Aguilera Paula· 1 shared Aida Shahrabi· 1 shared Alan Michael PittmaniD· 1 shared Andrew H. VuiD· 1 shared Anna C. ThomasiD· 1 shared Anneliese O. SpeakiD· 1 shared Anton Enright· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersGenetics

Jérémie NsengimanaORCID

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3 papers

Recent·Most cited

Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8

Hyunkyung Kong, Jiyeon Choi, Tongwu Zhang, Cathrin Gräwe, Mai Xu, Rohit Thakur, Hayley Sowards, Rebecca C. Hennessey, Andrew H. Vu, Jianxin Shi, D Timothy Bishop, Julia Newton-Bishop, Jérémie Nsengimana, Mark Martin Iles, Maria Teresa Landi, , Kevin M. Brown

The paper identifies rs3769823 as a functional variant near CASP8 influencing its expression in a cell-type specific manner and associated with multiple cancers.

bioRxiv · Jan 6, 2026 · PreprintGenetics

Inherited duplications of PPP2R3B promote naevi and melanoma via a novel C21orf91-driven proliferative phenotype

Satyamaanasa Polubothu, Lara Al-Olabi, Daniël A. Lionarons, Mark Harland, Anna C. Thomas, Stuart D. Horswell, Lilian Hunt, Nathan Wlodarchak, Aguilera Paula, Sarah Brand, Dale Bryant, Philip L. Beales, Cristina Carrera, Hui Chen, Greg S Elgar, , Veronica A. Kinsler

This study identifies inherited PPP2R3B duplications as a melanoma predisposing factor, revealing a C21orf91-driven proliferative phenotype in melanocytes.

Genetics in Medicine · Jun 18, 2021Peer-reviewedGenomics

A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination

Marco Ranzani, Kristel Kemper, Magali Michaut, Oscar Krijgsman, Nanne Aben, Vivek Iyer, Kim Wong, Theodoros I. Roumeliotis, Martin Del Castillo Velasco-Herrera, Jérémie Nsengimana, Gemma Turner, Nicola Thompson, Aida Shahrabi, Marcela Sjoberg, Mamunur Rashid, , David J. Adams

bioRxiv · Sep 28, 2017 · PreprintCancer Biology