Magali Michaut

Identifying biomarkers of anti-cancer drug synergy using multi-task learning

The paper uses multi-task learning to identify biomarkers of anti-cancer drug synergy using low-sample-size drug combination data from 85 cell lines and 167 drug combinations.

iTOP: Inferring the Topology of Omics Data

iTOP infers relationships between omics datasets using partial matrix correlations and identifies gene expression as a mediator between other datasets and drug response.

A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination

Genomic determinants of protein abundance variation in colorectal cancer cells

The paper quantifies proteomic and genomic variation in colorectal cancer cell lines to understand how mutations affect protein levels and drug responses.