Automodification of N-terminal serine residues in PARP2 impacts PARP2 release from DNA damage sites
Saurabh Singh Dhakar, Albert Galera‐Prat, Jin Cai, Julia Preißer, Tiila‐Riikka Kiema, Andreas G. Ladurner, L. Lehtiö
This study identifies serine residues in PARP2's N-terminus as targets of automodification, showing their role in PARP2 release from DNA damage sites via PARylation.
bioRxiv · Jul 1, 2025 · PreprintBiochemistry