Author

Jin Cai

Ludwig-Maximilians-Universität MünchenPrimary ORCID profile (0000-0001-9366-0793 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Jin CaiiD1 paper · Chinese Academy of Medical Sciences & Peking Union Medical College

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas G. LadurneriD· 2 shared Albert Galera‐PratiD· 1 shared Ben E. BlackiD· 1 shared Julia Preißer· 1 shared L. LehtiöiD· 1 shared Michael S. CoheniD· 1 shared Ramya BilluriD· 1 shared Saurabh Singh DhakariD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Andreas G. LadurnerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A Population-Specific PARP1 Gene Variation Modulates PARP Trapping

Jin Cai, Ramya Billur, Michael S. Cohen, Andreas G. Ladurner, Ben E. Black

The paper shows a population-specific PARP1 gene variant enhances the efficacy and toxicity of the PARPi drug talazoparib by altering its mechanism of action.

bioRxiv · Nov 11, 2025 · PreprintCancer Biology

Automodification of N-terminal serine residues in PARP2 impacts PARP2 release from DNA damage sites

Saurabh Singh Dhakar, Albert Galera‐Prat, Jin Cai, Julia Preißer, Tiila‐Riikka Kiema, Andreas G. Ladurner, L. Lehtiö

This study identifies serine residues in PARP2's N-terminus as targets of automodification, showing their role in PARP2 release from DNA damage sites via PARylation.

bioRxiv · Jul 1, 2025 · PreprintBiochemistry