Author
Max Planck Institute of BiochemistryORCID 0000-0003-3835-232XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jin Cai, Ramya Billur, Michael S. Cohen…·Ben E. Black
The paper shows a population-specific PARP1 gene variant enhances the efficacy and toxicity of the PARPi drug talazoparib by altering its mechanism of action.
Saurabh Singh Dhakar, Albert Galera‐Prat, Jin Cai…·L. Lehtiö
This study identifies serine residues in PARP2's N-terminus as targets of automodification, showing their role in PARP2 release from DNA damage sites via PARylation.
Magdalena Murawska, R.A. Greenstein, Tamás Schauer…·Sigurd J Braun
This study identifies FACT as a histone chaperone that promotes heterochromatin spreading by regulating histone turnover and H3K9 methylation states.
Matías Capella, Imke K. Mandemaker, Lucía Martín Caballero…·Sigurd J Braun
The paper shows that DNA damage triggers rDNA repeat relocation by phosphorylating the CLIP-cohibin complex, leading to SUMOylation and Cdc48/p97-mediated release from the nucleolus in yeast and human cells.