Author

Saurabh Singh Dhakar

University of OuluORCID 0000-0001-5444-8052Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Albert Galera‐PratiD· 2 shared Lari LehtiöiD· 2 shared Andreas G. LadurneriD· 1 shared Chiara BosettiiD· 1 shared Dionysis KampasisiD· 1 shared Ioannis K. KostakisiD· 1 shared Jin Cai· 1 shared Jo WaaleriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Albert Galera‐PratORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 1, 2025

Automodification of N-terminal serine residues in PARP2 impacts PARP2 release from DNA damage sites

Saurabh Singh Dhakar, Albert Galera‐Prat, Jin Cai…·L. Lehtiö

This study identifies serine residues in PARP2's N-terminus as targets of automodification, showing their role in PARP2 release from DNA damage sites via PARylation.

DOI 10.1101/2025.07.01.662498

humanproteomics

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BiochemistryEuropean Journal of Medicinal ChemistryPeer-reviewedFeb 15, 2025

Substitutions at the C-8 position of quinazolin-4-ones improve the potency of nicotinamide site binding tankyrase inhibitors

Chiara Bosetti, Dionysis Kampasis, Shoshy Alam Brinch…·Ioannis K. Kostakis

This study identifies C-8 position substitutions in quinazolin-4-ones that enhance the potency and selectivity of tankyrase inhibitors by improving interactions with TNKS2.

5 citations

humanexperimental assay

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