Metaplastic priming enables non-ionotropic NMDA receptor-mediated synaptic depotentiation in the hippocampus
Quinn Pauli, Juliet Arsenault, Samuel W. Fung, Amy J. Ramsey, Robert P. Bonin
This study shows that the temporal pattern of prior LTP induction affects the molecular pathways involved in depotentiation, with non-ionotropic NMDAR signaling required for compressed LTP depotentiation.
bioRxiv · Feb 28, 2025 · PreprintNeuroscience