Autophagy collaborates with apoptosis pathways to control myelination specificity and function
Tingxin Zhang, Han‐Gyu Bae, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Jumin Xue, Sabeen Wazir, Sara B. Mulinyawe, Jun Hee Kim, Lu O. Sun
This study shows autophagy promotes apoptosis in premyelinating oligodendrocytes to control myelination location, timing, and sheath thickness through the TFEB-PUMA-Bax/Bak pathway.
bioRxiv · Dec 31, 2022 · PreprintNeuroscience