Han‐Gyu Bae

This study generates a genetically labeled premyelinating oligodendrocyte mouse line to study their morphology, transcriptomics, and role in axon ensheathment and neuronal activity.

This study shows that Scn2a deletion in oligodendrocytes disrupts myelination and leads to auditory hypersensitivity in ASD.

This study shows autophagy promotes apoptosis in premyelinating oligodendrocytes to control myelination location, timing, and sheath thickness through the TFEB-PUMA-Bax/Bak pathway.

This study shows that the maternal gut microbiome affects brain development in mice, with persistent structural changes observed even after microbial reintroduction.

This study shows that Ermin deficiency causes myelin abnormalities and inflammation, leading to neurological deficits and increased susceptibility to demyelination, suggesting it as an 'inside-out' model for inflammatory dysmyelination.

The paper identifies molecular signatures and neurodevelopmental abnormalities in FMRP-deficient neurons derived from isogenic FMR1 knockout human embryonic stem cells.

This study identifies a dichotomic hypo-connected resting and hyper-responsive active phenotype in a mouse model of early tauopathy, with implications for Alzheimer's disease.