Author

Tingxin Zhang

The University of Texas Southwestern Medical CenterORCID 0000-0001-8831-9670Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aksheev BhambriiD· 2 shared Daniela BarbosaiD· 2 shared Lu O. SuniD· 2 shared Han‐Gyu BaeiD· 1 shared Jumin Xue· 1 shared Jun Hee KimiD· 1 shared Sabeen WaziriD· 1 shared Sara B. Mulinyawe· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Aksheev BhambriORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 11, 2026

Oligodendrocyte ER-phagy Restricts Excessive Myelination by Degrading Sphingolipid Synthases

Tingxin Zhang, Daniela Barbosa, Aksheev Bhambri, Lu O. Sun

This study identifies ER-phagy as a negative regulator of myelin sheath thickness by degrading sphingolipid synthases in oligodendrocytes, preventing excessive myelination.

DOI 10.64898/2026.10.04.756522

mouseexperimental assay

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NeurosciencebioRxivPreprintDec 31, 2022

Autophagy collaborates with apoptosis pathways to control myelination specificity and function

Tingxin Zhang, Han‐Gyu Bae, Aksheev Bhambri…·Lu O. Sun

This study shows autophagy promotes apoptosis in premyelinating oligodendrocytes to control myelination location, timing, and sheath thickness through the TFEB-PUMA-Bax/Bak pathway.

1 citation

mousestatistical model

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