Stem cell-free therapy for glaucoma to preserve vision
A. Kumar, S. Xiong, M. Zhou, W. Chen, E. Yang, A. Price, L. Le, Y. Zhang, L. Florens, M. Washburn, A. Kumar, Y. Li, Y. Xu, K. L. Lathrop, K. A. Davoli, , Y. Du
This study demonstrates that stem cell-derived secretome reduces intraocular pressure and protects retinal ganglion cells in glaucoma models through COX2-PGE2 pathway activation and extracellular matrix remodeling.
bioRxiv · Jun 18, 2021 · PreprintCell Biology