Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
E. Sutherland, C. J. Harding, T. M. Y. D. Monceau De Bergendal, G. J. Florence, K. Ackermann, B. E. Bode, S. Synowksy, R. Sundaramoorthy, C. M. Czekster
This study characterizes the structure and mechanism of NdasCDO, a flavin-dependent cyclodipeptide oxidase, revealing its promiscuous substrate scope and reaction mechanism.
bioRxiv · Jul 24, 2024Biochemistry