K. B. Busch

Tagging of Exo70 at the N-terminus compromises its assembly with the exocyst complex and changes its spatiotemporal behavior at the plasma membrane

This paper shows that N-terminal tagging of Exo70 disrupts its assembly with the exocyst complex and alters its spatiotemporal behavior at the plasma membrane.

Mdivi-1 affects neuronal activity by inhibition of Complex I and respiratory supercomplex assembly

This paper identifies that Mdivi-1 inhibits mitochondrial complex I, disrupts supercomplex assembly, and impairs neuronal activity by affecting ATP production and calcium homeostasis.

LUBAC assembles a signaling platform at mitochondria for signal amplification and shuttling of NF-ĸB to the nucleus

This study shows that LUBAC assembles at mitochondria to amplify and shuttle NF-κB signals to the nucleus during TNF activation.

Mitochondrial F1FO ATP synthase determines the local proton motive force in cristae tips

This study shows that mitochondrial F1FO ATP synthase controls the local proton motive force in cristae tips and that IF1 prevents reverse ATP synthase activity under OXPHOS conditions.