Author

K. C. Whitley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

R. E. MacPherson· 3 shared A. J. MacNeil· 2 shared B. D. Roy· 2 shared C. J. Watson· 2 shared J. L. Braun· 2 shared S. I. Hamstra· 2 shared V. Fajardo· 2 shared A. A. Marais· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersPhysiology

R. E. MacPherson

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3 papers

Recent·Most cited

GSK3 inhibition improves skeletal muscle function and whole-body metabolism in the severe DBA/2J mdx mouse model

B. M. Marcella, B. Hockey, J. L. Braun, K. C. Whitley, M. S. Geromella, R. W. Baranowski, C. J. Watson, S. Silvera, S. I. Hamstra, L. J. Wasilewicz, R. W. Crozier, A. A. Marais, R. Vandenboom, B. D. Roy, A. J. MacNeil, , V. Fajardo

This study shows that GSK3 inhibition improves skeletal muscle function and insulin sensitivity in mdx mice, either alone or combined with exercise.

bioRxiv · Feb 16, 2022 · PreprintPhysiology

Kynurenine metabolism is altered in mdx mice: a potential muscle to brain connection

E. N. Copeland, K. C. Whitley, C. J. Watson, B. J. Baranowski, N. Kurgan, A. J. MacNeil, R. E. MacPherson, V. A. Fajardo, D. J. Allison

This study shows that KYN metabolism is altered in D2 mdx mice, with reduced KYNA and KYNA:KYN ratio and anxiety-like behaviors, suggesting a link between muscle disease and brain metabolism.

bioRxiv · Jan 14, 2022Physiology

SERCA function is impaired in skeletal and cardiac muscles from young DBA/2J mdx mice

R. E. Cleverdon, K. C. Whitley, D. M. Marko, S. I. Hamstra, J. L. Braun, B. D. Roy, R. E. MacPherson, V. Fajardo

This study compares SERCA function in skeletal and cardiac muscles of young D2 and C57 mdx mice, finding more severe impairments in D2 mdx mice.

bioRxiv · Oct 25, 2021Pathology