Author

K. D. Buchan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:zebrafish· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Kolata· 2 shared M. van Gent· 2 shared N. V. Ogryzko· 2 shared S. A. Renshaw· 2 shared S. J. Foster· 2 shared T. K. Prajsnar· 2 shared A. E. Hohlt· 1 shared A. R. Flores· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

J. Kolata

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Author profile →

3 papers

Recent·Most cited

LiaR-dependent gene expression contributes to antimicrobial responses in group A Streptococcus

L. A. Vega, M. A. Sanson, P. Mukherjee, G. A. Morrison, K. D. Buchan, A. E. Hohlt, A. R. Flores

This study identifies the LiaFSR regulon in Group A Streptococcus and shows how phosphorylated LiaR regulates virulence and AMP resistance via SpxA2 and other genes.

bioRxiv · Apr 4, 2024 · PreprintMicrobiology

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model.

K. D. Buchan, M. van Gent, T. K. Prajsnar, N. V. Ogryzko, N. de Jong, J. Kolata, S. J. Foster, J. A. van Strijp, S. A. Renshaw

This study shows human-specific S. aureus toxins enhance pathogenicity in a humanised zebrafish model expressing the human C5a receptor.

bioRxiv · Feb 18, 2020Immunology

A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase

K. D. Buchan, T. K. Prajsnar, N. V. Ogryzko, N. W. de Jong, M. van Gent, J. Kolata, S. J. Foster, J. A. G. A. Van Strijp, S. A. Renshaw

This paper introduces a transgenic zebrafish line expressing human MPO with a fluorescent tag to study neutrophil granule dynamics in vivo.

bioRxiv · Mar 20, 2019Immunology