Author

M. van Gent

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:zebrafish· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

J. Kolata· 2 shared K. D. Buchan· 2 shared N. V. Ogryzko· 2 shared S. A. Renshaw· 2 shared S. J. Foster· 2 shared T. K. Prajsnar· 2 shared C. Chiang· 1 shared D. Acharya· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

J. Kolata

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Author profile →

3 papers

Recent·Most cited

ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease

G. Liu, J.-H. Lee, Z. M. Parker, D. Acharya, J. J. Chiang, M. van Gent, W. Riedl, M. E. Davis-Gardner, E. Wies, C. Chiang, M. U. Gack

This study shows ISG15 is essential for MDA5-mediated antiviral responses and is counteracted by SARS-CoV-2's PLpro protease.

bioRxiv · Oct 26, 2020Immunology

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model.

K. D. Buchan, M. van Gent, T. K. Prajsnar, N. V. Ogryzko, N. de Jong, J. Kolata, S. J. Foster, J. A. van Strijp, S. A. Renshaw

This study shows human-specific S. aureus toxins enhance pathogenicity in a humanised zebrafish model expressing the human C5a receptor.

bioRxiv · Feb 18, 2020Immunology

A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase

K. D. Buchan, T. K. Prajsnar, N. V. Ogryzko, N. W. de Jong, M. van Gent, J. Kolata, S. J. Foster, J. A. G. A. Van Strijp, S. A. Renshaw

This paper introduces a transgenic zebrafish line expressing human MPO with a fluorescent tag to study neutrophil granule dynamics in vivo.

bioRxiv · Mar 20, 2019Immunology