High prevalence and dependence of centrosome clustering in mesenchymal tumors and leukemia
N. M. Marin, G. Marteil, N. C. Fresmann, B. P. de Almeida, K. Dores, R. Fragoso, J. C. Vaz, J. B. P. Leal, J. P. Taborda Barata, S. A. Godinho, N. L. Barbosa-Morais, M. Bettencourt-Dias
This study shows centrosome clustering is common in mesenchymal tumors and leukemia, especially in cells with epithelial-to-mesenchymal transition features, and suggests targeting this process could treat certain leukemias.
bioRxiv · Mar 13, 2023 · PreprintCancer Biology