Author

K. E. W. Namitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

M. S. Cosgrove· 2 shared A. J. Clark· 1 shared A. Vaidya· 1 shared B. C. Taylor· 1 shared B. D. Strahl· 1 shared B. Hellner· 1 shared C. Cummings· 1 shared E. F. Patteson· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

M. S. Cosgrove

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3 papers

Recent·Most cited

Characterization of Recombinant Human Lactoferrin Expressed in Komagataella Phaffii

X. Lu, C. Cummings, U. A. Osuala, N. H. Yennawar, K. E. W. Namitz, B. Hellner, P. B. Besada-Lombana, R. D. Peterson, A. J. Clark

This study characterizes recombinant human lactoferrin produced in yeast, confirming its sequence, purity, glycosylation, structure, and thermal stability similar to native human milk lactoferrin.

bioRxiv · Jan 9, 2024 · PreprintBiophysics

An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability

K. Jain, M. R. Marunde, J. M. Burg, S. L. Gloor, F. M. Joseph, K. F. Poncha, Z. B. Gillespie, K. L. Rodriguez, I. K. Popova, N. W. Hall, A. Vaidya, S. A. Howard, H. F. Taylor, L. Mukhsinova, U. C. Onuoha, , B. D. Strahl

The paper shows that H3 tail acetylation enhances accessibility of both H3K4 methyl readers and writers, revealing an acetylation-mediated chromatin switch that modulates H3K4 methylation read-write capability.

bioRxiv · Feb 28, 2022Biochemistry

Hierarchical assembly of the MLL1 core complex within a biomolecular condensate regulates H3K4 methylation

K. E. W. Namitz, S. Tan, M. S. Cosgrove

This study investigates how the MLL1 core complex assembles within biomolecular condensates to regulate H3K4 methylation, proposing a swinging-domain model for spatiotemporal control.

bioRxiv · Dec 10, 2019 · PreprintBiochemistry