Author

M. R. Marunde

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:ChIP-seq· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

M.-C. Keogh· 3 shared I. K. Popova· 2 shared M. A. Cheek· 2 shared M. J. Meiners· 2 shared N. W. Hall· 2 shared A. Allali-Hassani· 1 shared A. Bolotokova· 1 shared A. Dest· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersBiochemistry

M.-C. Keogh

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Author profile →

3 papers

Recent·Most cited

An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability

K. Jain, M. R. Marunde, J. M. Burg, S. L. Gloor, F. M. Joseph, K. F. Poncha, Z. B. Gillespie, K. L. Rodriguez, I. K. Popova, N. W. Hall, A. Vaidya, S. A. Howard, H. F. Taylor, L. Mukhsinova, U. C. Onuoha, , B. D. Strahl

The paper shows that H3 tail acetylation enhances accessibility of both H3K4 methyl readers and writers, revealing an acetylation-mediated chromatin switch that modulates H3K4 methylation read-write capability.

bioRxiv · Feb 28, 2022Biochemistry

Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

D. Dilworth, R. P. Hanley, R. Ferreira de Freitas, A. Allali-Hassani, M. Zhou, N. Mehta, M. R. Marunde, S. Ackloo, E. Marcon, F. Li, I. Chau, A. Bolotokova, S. Qin, M. Lei, Y. Liu, , M. Schapira

The paper develops a chemical probe, UNC6934, that targets the PWWP1 domain of NSD2, revealing cooperative control of NSD2 localization through chromatin reader domains.

bioRxiv · Mar 5, 2021 · PreprintCell Biology

Structural insights into the recognition of mono- and di-acetylated histones by the ATAD2B bromodomain

J. T. Lloyd, K. McLaughlin, M. Y. Lubula, J. C. Gay, A. Dest, C. Gao, M. Phillips, M. Tonelli, G. Cornilescu, M. R. Marunde, C. M. Evans, S. P. Boyson, S. Carlson, M.-C. Keogh, J. L. Markley, , K. C. Glass

This study investigates the ligand specificity of the ATAD2B bromodomain, showing it binds mono- and di-acetylated histones and identifies structural features critical for this recognition.

bioRxiv · May 12, 2020 · PreprintBiochemistry