Selective inhibition of PfATP6 by artemisinins and identification of new classes of inhibitors after expression in yeast
C. M. Moore, J. Wang, Q. Lin, P. E. Ferreira, M. A. Avery, K. Elokely, H. M. Staines, S. Krishna
The paper develops a yeast-based screening tool to identify PfATP6 inhibitors, confirming artemisinins target PfATP6 and discovering new inhibitor classes.
bioRxiv · Oct 27, 2021 · PreprintPharmacology & Toxicology