Author

K. Eyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:cell-cell communication· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

J. Baudry· 3 shared A. Linder· 2 shared K. Portmann· 2 shared A. Perima· 1 shared A. Robbins· 1 shared A. Sokal· 1 shared A. Vandenberghe· 1 shared B. Iannascoli· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

J. Baudry

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5 papers

Recent·Most cited

Single-B cell analysis correlates high-lactate secretion with stress and increased apoptosis

O. T. M. Bucheli, D. Rodrigues, K. Portmann, A. Linder, M. Thoma, C. Halin, K. Eyer

The paper correlates high lactate secretion in B cells with stress and increased apoptosis, using single-cell transcriptomics and metabolic flux analysis in mice.

bioRxiv · Sep 1, 2023Immunology

Stimulation-induced cytokine polyfunctionality as a dynamic concept

K. Portmann, A. Linder, K. Eyer

This study investigates cytokine polyfunctionality dynamics in PBMCs using a single-cell microfluidic platform, revealing distinct secretion patterns and reduced polyfunctionality with prolonged stimulation.

bioRxiv · Jul 18, 2023Immunology

Single cell profiling reveals functional heterogeneity and serial killing in human peripheral and ex vivo-generated CD34+ progenitor derived Natural Killer cells

N. Subedi, L. P. Verhagen, P. de Jonge, L. C. Van Eyndhoven, M. C. van Turnhout, V. Koomen, J. Baudry, K. Eyer, H. Dolstra, J. Tel

This study uses single-cell analysis to identify functional heterogeneity and serial killing in NK cells from peripheral blood and ex vivo-generated CD34+ progenitors.

bioRxiv · Jan 24, 2022Immunology

Single-cell analyses of immune thrombocytopenic patients reveal multiorgan dissemination of high-affinity autoreactive plasma cells

P. Canales Herrerias, E. Crickx, M. Broketa, A. Sokal, G. Chenon, I. Azzaoui, A. Vandenberghe, A. Perima, B. Iannascoli, O. Richard-Le Goff, C. Castrillon, G. Mottet, D. Sterlin, A. Robbins, M. Michel, , P. Bruhns

This study identifies high-affinity autoreactive plasma cells in multiple organs of ITP patients, showing treatment resistance and suggesting therapy failure mechanisms.

bioRxiv · Jun 29, 2021 · PreprintImmunology

Quantitative modeling of the effect of antigen dosage on B-cell affinity distributions in maturating germinal centers

M. Molari, K. Eyer, J. Baudry, S. Cocco, R. Monasson

This study models how antigen dosage affects B-cell affinity distributions in germinal centers and shows non-monotonic relationships between antigen levels and average affinity.

bioRxiv · May 22, 2020Immunology