Author

K. G. Hardwick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:fungi (other)· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

I. Clark· 2 shared I. Leontiou· 2 shared A. A. Jeyaprakash· 1 shared A. P. Suresh· 1 shared C. Spanos· 1 shared K. Aktar· 1 shared K. Bhat· 1 shared K. Das· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

I. Clark

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3 papers

Recent·Most cited

The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans

S. D. Polisetty, K. Bhat, K. Das, I. Clark, K. G. Hardwick, K. Sanyal

This study shows that Sgo1 maintains SAC signals in Cryptococcus neoformans by regulating Aurora B kinase and PP1 levels at kinetochores, independent of Bub1 kinase activity.

bioRxiv · Feb 28, 2024 · PreprintCell Biology

Bub1 kinase acts as a signalling hub for the entire Cryptococcus neoformans spindle assembly checkpoint pathway

I. Leontiou, T. Davies, I. Clark, K. Aktar, A. P. Suresh, M. A. Abad, C. Spanos, K.-T. Lee, Y.-S. Bahn, A. A. Jeyaprakash, K. G. Hardwick

This study identifies CnBub1 as a multifunctional protein in Cryptococcus neoformans that integrates both Bub1 and Mad3/BubR1 functions in the spindle assembly checkpoint.

bioRxiv · Sep 21, 2022 · PreprintCell Biology

In vivo, regulated reconstitution of spindle checkpoint arrest and silencing through chemical-induced dimerisation

P. Amin, S. Soper ni Chafraidh, I. Leontiou, K. G. Hardwick

This paper uses chemical-induced dimerisation to reconstitute spindle checkpoint arrest in fission yeast and shows that checkpoint silencing depends on PP1Dis2 recruitment.

bioRxiv · Sep 10, 2018Cell Biology