MicrobiologybioRxiv
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy
E.-I. Koh, P. O. Oluoch, N. Ruecker…·C. M. Sassetti
This study maps chemical-genetic interactions in Mycobacterium tuberculosis to identify how carbon metabolism and cell wall structure affect drug efficacy, revealing environment-dependent and -independent interactions.
DOI 10.1073/pnas.2201632119