Author

K. Hayer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Bhattacharyya· 1 shared C. Bassing· 1 shared C. H. June· 1 shared C. Miot· 1 shared C. R. Good· 1 shared E. Behrens· 1 shared E. Culberson· 1 shared E. J. Orlando· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Bhattacharyya

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Author profile →

2 papers

Recent·Most cited

The RAG1 Ubiquitin Ligase Domain Enhances Assembly and Selection of T Cell Receptor Genes to Restrain the Autoimmune Hazard of Generating T Cell Receptor Diversity

T. Burn, C. Miot, S. Gordon, E. Culberson, T. Diamond, P. Kreiger, K. Hayer, A. Bhattacharyya, J. Jones, C. Bassing, E. Behrens

This study shows that the RAG1 ubiquitin ligase domain enhances TCR gene assembly and selection, reducing autoimmune risk in mice.

bioRxiv · Jan 4, 2021 · PreprintImmunology

Impaired tumor death receptor signaling drives resistance to CAR T cell therapy

N. Singh, O. Shestova, P. Ravikumar, K. Hayer, S. J. Hong, E. J. Orlando, K. T. Mueller, C. R. Good, S. L. Berger, O. Shalem, M. D. Weitzman, S. A. Grupp, C. H. June, S. Gill, M. Ruella

This study identifies impaired death receptor signaling as a driver of resistance to CAR T cell therapy in B-cell leukemia by showing its role in tumor survival and T cell dysfunction.

bioRxiv · May 5, 2019 · PreprintImmunology