Author

K. Helena-Bueno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:bacteria (other)· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

C. R. Brown· 4 shared S. V. Melnikov· 3 shared A. van den Elzen· 1 shared D. Nicholson· 1 shared J. Barandun· 1 shared J. Panek· 1 shared L. Schierholz· 1 shared M. Salamina· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersEvolutionary Biology

C. R. Brown

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Author profile →

4 papers

Recent·Most cited

A conserved ribosomal protein has entirely dissimilar structures in different organisms

L. Schierholz, C. R. Brown, K. Helena-Bueno, V. N. Uversky, R. Hirt, J. Barandun, S. V. Melnikov

The paper shows that the ribosomal protein msL1/msL2 has conserved location but entirely different structures across species, suggesting evolutionary fold switching driven by changes in rRNA binding sites.

bioRxiv · Sep 21, 2022Evolutionary Biology

Ribosomes as molecular thermometers: metal-binding sites in ribosomal proteins are robust indicators of bacterial adaptation to heat and cold

A. van den Elzen, K. Helena-Bueno, C. R. Brown, S. V. Melnikov

The paper identifies temperature-adaptive residues in ribosomal proteins that can estimate bacterial optimal growth temperatures using minimal genomic data.

bioRxiv · Sep 9, 2022 · PreprintEvolutionary Biology

Gosha: a database of organisms with defined optimal growth temperatures

K. Helena-Bueno, C. R. Brown, S. Melnikov

Gosha is a database that compiles optimal growth temperatures for 25,324 species, enabling studies of molecular adaptations to temperature variations.

bioRxiv · Dec 21, 2021 · PreprintEvolutionary Biology

'Lose-to-gain' adaptation to genome decayin the structure of the smallest eukaryotic ribosomes

D. Nicholson, M. Salamina, J. Panek, K. Helena-Bueno, C. R. Brown, R. P. Hirt, N. A. Ranson, S. V. Melnikov

This study uses cryo-EM and evolutionary analysis to show how E. cuniculi ribosomes adapt to genome decay through structural innovations that enable extreme rRNA reduction without losing ribosome function.

bioRxiv · Sep 6, 2021 · PreprintEvolutionary Biology