V. N. Uversky

The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction.

This study identifies the PALB2 DNA-binding domain as an intrinsically disordered region that promotes DNA compaction through oligomerization, revealing a novel strand exchange mechanism.

A conserved ribosomal protein has entirely dissimilar structures in different organisms

The paper shows that the ribosomal protein msL1/msL2 has conserved location but entirely different structures across species, suggesting evolutionary fold switching driven by changes in rRNA binding sites.

An exploration of the SARS-CoV-2 spike receptor binding domain (RBD), a complex palette of evolutionary and structural features

The paper analyzes the SARS-CoV-2 spike RBD using evolutionary and structural methods to identify potential druggable regions.

Tudor staphylococcal nuclease acts as a docking platform for stress granule components in Arabidopsis thaliana

This study identifies TSN as a docking platform for stress granule components in Arabidopsis thaliana, revealing its role in stress signaling and SG formation.

Granulins modulate liquid-liquid phase separation and aggregation of TDP-43 C-terminal domain

This study shows GRNs-3 and -5 interact with TDP-43CTD to modulate its aggregation and stress granule formation in vitro, linking PGRN loss to FTLD and ALS.