Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
T. C. Passchier, J. B. R. White, D. P. Maskell, M. J. Byrne, N. A. Ranson, T. A. Edwards, J. N. Barr
The paper reports the cryoEM structure of Hendra henipavirus nucleoprotein bound to RNA, revealing unique interactions in its multimeric assembly and insights into paramyxoviral nucleocapsid architecture.
bioRxiv · Dec 7, 2023 · PreprintMicrobiology
J. Machin, A. C. Kali, N. A. Ranson, S. E. Radford
The paper investigates how lipid charge asymmetry affects the folding of bacterial outer membrane proteins (OMPs) and identifies key residues involved in this process.
bioRxiv · Apr 20, 2023 · PreprintBiophysics
N. Louros, M. Wilkinson, G. Tsaka, M. Ramakers, C. Morelli, T. Garcia, R. U. Gallardo, S. D'Haeyer, V. Goossens, D. Audenaert, D. R. Thal, N. A. Ranson, S. E. Radford, F. Rousseau, J. Schymkowitz
The paper identifies a C-terminal tau peptide that adopts polymorphic conformations contributing to disease-specific tau filament folds and propagation.
bioRxiv · Oct 24, 2022 · PreprintBiophysics
J. B. White, A. Silale, M. C. Feasey, T. Heunis, Y. Zhu, H. Zheng, A. Gajbhiye, S. Firbank, A. Basle, M. Trost, D. N. Bolam, N. A. Ranson, B. van den Berg
The paper identifies utilisomes as stable glycan-utilising complexes in Bacteroides thetaiotaomicron, revealing their structure and mechanism of substrate capture via cryo-EM.
bioRxiv · Aug 15, 2022Microbiology
N. J. Stonehouse, N. J. Kingston, K. Grehan, J. S. Snowden, M. Hassall, J. Alzahrani, G. C. Paesen, L. Sherry, C. R. Hayward, A. Roe, S. Stephen, D. C. Tomlinson, A. Zeltina, K. J. Doores, N. A. Ranson, , D. J. Rowlands
VelcroVax is a vaccine platform that enhances antibody titres against a viral glycoprotein in mice by combining a modified VLP with a SUMO-tagged antigen.
bioRxiv · Apr 22, 2022 · PreprintImmunology
L. Marr, D. Biswas, L. A. Daly, C. Browning, S. Vial, D. P. Maskell, C. Hudson, J. Pollard, J. Bertrand, N. A. Ranson, H. Khatter, C. E. Eyers, K. Sakamoto, E. Zeqiraj
The paper describes the cryo-EM structure of phosphorylated glycogen synthase and its interaction with glycogenin, revealing mechanisms of GS autoinhibition and regulation.
bioRxiv · Nov 14, 2021Biochemistry
N. Patel, S. Clark, E. U. Weiss, C. P. Mata, J. Bohon, E. Farquhar, D. P. Maskell, N. A. Ranson, R. Twarock, P. G. Stockley
The paper investigates RNA sequence/structure motifs regulating HBV genome assembly in vitro, showing their role in nucleocapsid formation and confirming interactions via X-ray RNA footprinting.
bioRxiv · Sep 8, 2021Microbiology
D. Nicholson, M. Salamina, J. Panek, K. Helena-Bueno, C. R. Brown, R. P. Hirt, N. A. Ranson, S. V. Melnikov
This study uses cryo-EM and evolutionary analysis to show how E. cuniculi ribosomes adapt to genome decay through structural innovations that enable extreme rRNA reduction without losing ribosome function.
bioRxiv · Sep 6, 2021 · PreprintEvolutionary Biology
J. S. Snowden, J. Alzahrani, L. Sherry, M. Stacey, D. J. Rowlands, N. A. Ranson, N. J. Stonehouse
The paper determines the structure of P. pastoris fatty acid synthase using cryoEM, identifying structural differences from S. cerevisiae FAS and resolving the mobile ACP domain.
bioRxiv · Jan 27, 2021Microbiology
J. S. Snowden, D. L. Hurdiss, O. O. Adeyemi, N. A. Ranson, M. R. Herod, N. J. Stonehouse
This study uses cryo-EM to reveal the dynamic conformational changes in murine norovirus capsids, showing flexibility in protruding domains that impact virion stability and infectivity.
bioRxiv · Jul 4, 2019 · PreprintMicrobiology