Direct optical measurement of intra-molecular distances down to the Angstrom scale
S. J. Sahl, J. Matthias, K. Inamdar, T. A. Khan, M. Weber, S. Becker, C. Griesinger, J. Broichhagen, S. W. Hell
This paper demonstrates that MINFLUX fluorescence nanoscopy can measure intra-molecular distances down to 1 Angstrom with high precision, validated using known protein distances and subunit orientations.
bioRxiv · Jul 7, 2023 · PreprintBiophysics