D. Muriaux

The multifunction Coxiella effector Vice stimulates macropinocytosis and interferes with the ESCRT machinery

This study identifies the Coxiella effector Vice as a protein that manipulates host cell lipid composition and cellular pathways to form the Coxiella-containing vacuole.

Comprehensive Analysis of Neutrophil Immunomodulatory Properties and FcR Dynamics in Health and HIV-1 Infection and Therapy

The paper examines neutrophil immunomodulatory properties and FcR dynamics in HIV-1 infection and therapy, finding altered cytokine production and FcR expression in PLWH.

Tetraspanin CD82 maintains HTLV-1 biofilm polarization and is required for efficient viral transmission

This study identifies CD82 as a key tetraspanin that maintains HTLV-1 biofilm polarization and enhances viral transmission through cell-to-cell contact.

Human airway ex vivo models: new tools to study the airway epithelial cell response to SARS-CoV-2 infection

The paper uses ALI and iALI models to study SARS-CoV-2 infection effects on airway epithelial cells, finding increased interferon and inflammatory gene expression and epithelial damage.

Specific targeting and clustering of Phosphatidylserine lipids by RSV M protein is critical for virus particle production

This study shows RSV M protein binds phosphatidylserine lipids, promoting viral assembly, and identifies lipid interactions critical for virus production.

HIV-1 diverts actin debranching mechanismsfor particle assembly and release in CD4 Tlymphocytes.

This study shows HIV-1 uses actin debranching to enhance virus assembly and release by recruiting Arpin in CD4 T lymphocytes.

Quantification of membrane binding and diffusion using Fluorescence Correlation Spectroscopy diffusion laws

This study develops an FCS diffusion law to quantify membrane binding and diffusion of proteins, validated with simulations and experiments on retroviral Gag proteins.

Optimized production and fluorescent labelling of SARS-CoV-2 Virus-Like-Particles to study virus assembly and entry.

This paper optimizes the production of SARS-CoV-2 Virus-Like Particles (VLPs) and demonstrates their fluorescent labeling for studying virus assembly and entry mechanisms.

Reorganization of F-actin nanostructures is required for the late phases of SARS-CoV-2 replication in pulmonary cells.

This study shows that reorganization of F-actin nanostructures is critical for late stages of SARS-CoV-2 replication in pulmonary cells, with alpha-actinins playing a key role.

Low selectivity index of ivermectin and macrocyclic lactones on SARS-CoV2 replication in vitro argues against their therapeutic use for COVID-19.

This study evaluates the anti-SARS-CoV-2 activity of ivermectin and other macrocyclic lactones in vitro, finding low selectivity indices that suggest limited therapeutic potential for COVID-19.

Full assembly of HIV-1 particles requires assistance of the membrane curvature factor IRSp53.

This study shows that IRSp53 assists HIV-1 in forming membrane curvature necessary for complete particle assembly.

Direct visualization of native infectious SARS-CoV-2 and its inactivation forms using high resolution Atomic Force Microscopy

This paper uses atomic force microscopy to visualize native and inactivated SARS-CoV-2 viruses, showing their structural changes after formaldehyde treatment.

HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly.

Self assembly of HIV-1 Gag protein on lipid membranes generates PI(4,5)P2/Cholesterolnanoclusters.

This study shows HIV-1 Gag self-assembly creates PIP2/cholesterol nanoclusters on lipid membranes during virus assembly.