Author

K. J. Brennand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Seah· 2 shared A. Murphy· 1 shared B. Javidfar· 1 shared B. Kassim· 1 shared B. McCarthy· 1 shared B. tenOever· 1 shared C. J. Hunter· 1 shared C. P. O'Shea· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPathology

C. Seah

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Author profile →

2 papers

Recent·Most cited

Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neurons

M. S. Breen, T. Rusielewicz, H. N. Bader, C. Seah, C. Xu, C. J. Hunter, B. McCarthy, M. Chattopadhyay, F. Desarnaud, I. Makotkine, J. D. Flory, L. M. Bierer, M. Staniskyte, NYSCF Global Array Team, S. A. Noggle, , R. Yehuda

The paper examines gene x environment interactions in PTSD by analyzing glucocorticoid-induced transcriptomics in human neurons and blood cells from veterans with and without PTSD.

bioRxiv · Mar 1, 2021 · PreprintPathology

Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection

K. Dobrindt, D. A. Hoagland, C. Seah, B. Kassim, C. P. O'Shea, M. Iskhakova, M. Fernando, P. M. Deans, S. K. Powell, B. Javidfar, A. Murphy, C. Peter, R. Moeller, M. Fernandez Garcia, M. Kimura, , K. J. Brennand

This study shows that a common genetic variant in the FURIN gene affects SARS-CoV-2 infection in vitro, suggesting genetic factors contribute to clinical variability in COVID-19.

bioRxiv · Sep 20, 2020Cell Biology