Author

D. A. Hoagland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. tenOever· 2 shared R. Moeller· 2 shared A. Baez Vazquez· 1 shared A. C. Borczuk· 1 shared A. Kodra· 1 shared A. Lachmann· 1 shared A. Lai· 1 shared A. Ma'ayan· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

B. tenOever

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Macrophages control pathological interferon responses during viral respiratory infection

D. A. Hoagland, P. Rodriguez-Morales, A. O. Mann, S. Yu, A. Lai, A. Baez Vazquez, S. D. Pope, J. Lim, S. Li, X. Zhang, M. O. Li, R. Medzhitov, R. A. Franklin

This study identifies macrophage-derived Oncostatin M as a critical regulator of type I interferon responses during viral respiratory infection, preventing excessive inflammation.

bioRxiv · Dec 16, 2023Immunology

SARS-CoV-2 infection results in lasting and systemic perturbations post recovery

J. J. Frere, R. A. Serafini, K. D. Pryce, M. Zazhytska, K. Oishi, I. Golynker, M. Panis, J. Zimering, S. Horiuchi, D. A. Hoagland, R. Moller, A. Ruiz, J. B. Overdevest, A. Kodra, P. D. Canoll, , B. tenOever

This study compares short- and long-term systemic responses to SARS-CoV-2 and IAV in golden hamsters, finding persistent inflammation in olfactory tissues post-recovery.

bioRxiv · Jan 18, 2022Microbiology

Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection

K. Dobrindt, D. A. Hoagland, C. Seah, B. Kassim, C. P. O'Shea, M. Iskhakova, M. Fernando, P. M. Deans, S. K. Powell, B. Javidfar, A. Murphy, C. Peter, R. Moeller, M. Fernandez Garcia, M. Kimura, , K. J. Brennand

This study shows that a common genetic variant in the FURIN gene affects SARS-CoV-2 infection in vitro, suggesting genetic factors contribute to clinical variability in COVID-19.

bioRxiv · Sep 20, 2020Cell Biology

Modulating the transcriptional landscape of SARS-CoV-2 as an effective method for developing antiviral compounds

D. A. Hoagland, D. J. B. Clarke, R. Moeller, Y. Han, L. Yang, M. L. Wojciechowicz, A. Lachmann, K. Y. Oguntuyo, C. Stevens, B. Lee, S. Chen, A. Ma'ayan, B. R. tenOever

This study identifies antiviral compounds that reduce SARS-CoV-2 viral load by counteracting the virus-induced transcriptional landscape, without affecting viral entry or host antiviral response.

bioRxiv · Jul 12, 2020 · PreprintMicrobiology