Author

B. tenOever

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2

Frequent Co-Authors

M. Panis· 3 shared B. Lee· 2 shared D. A. Hoagland· 2 shared K. Oishi· 2 shared R. Moeller· 2 shared A. C. Borczuk· 1 shared A. Kodra· 1 shared A. Murphy· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

M. Panis

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

SARS-CoV-2 infection results in lasting and systemic perturbations post recovery

J. J. Frere, R. A. Serafini, K. D. Pryce, M. Zazhytska, K. Oishi, I. Golynker, M. Panis, J. Zimering, S. Horiuchi, D. A. Hoagland, R. Moller, A. Ruiz, J. B. Overdevest, A. Kodra, P. D. Canoll, , B. tenOever

This study compares short- and long-term systemic responses to SARS-CoV-2 and IAV in golden hamsters, finding persistent inflammation in olfactory tissues post-recovery.

bioRxiv · Jan 18, 2022Microbiology

Nipah virus Bangladesh infection elicits organ-specific innate and inflammatory responses in the marmoset model

C. S. Stevens, J. Lowry, T. Juelich, C. Atkins, K. Johnson, J. K. Smith, M. Panis, T. Ikegame, B. tenOever, A. N. Freiberg, B. Lee

This study investigates NiV Bangladesh infection in marmosets, revealing organ-specific innate and inflammatory responses through RNA-seq analysis.

bioRxiv · Oct 11, 2021Microbiology

Stress granules are shock absorbers that prevent excessive innate immune responses to dsRNA

S. Hur, M. Paget, C. Cadena, S. Ahmad, H. Wang, T. Jordan, E. Kim, Q. Zhang, B. Koo, S. Lyons, P. Ivanov, B. tenOever, X. Mu

This study shows stress granules regulate immune responses to dsRNA by preventing excessive inflammation and viral replication.

bioRxiv · Apr 26, 2021Immunology

Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection

K. Dobrindt, D. A. Hoagland, C. Seah, B. Kassim, C. P. O'Shea, M. Iskhakova, M. Fernando, P. M. Deans, S. K. Powell, B. Javidfar, A. Murphy, C. Peter, R. Moeller, M. Fernandez Garcia, M. Kimura, , K. J. Brennand

This study shows that a common genetic variant in the FURIN gene affects SARS-CoV-2 infection in vitro, suggesting genetic factors contribute to clinical variability in COVID-19.

bioRxiv · Sep 20, 2020Cell Biology

An inability to maintain the ribonucleoprotein genomic structure is responsible for host detection of negative-sense RNA viruses

D. Blanco-Melo, B. E. Nilsson-Payant, S. Uhl, B. Escudero, S. Olschewski, P. Thibault, M. Panis, M. Rosenthal, C. Munoz-Fontela, B. Lee, B. tenOever

The paper shows that limiting nucleoprotein (NP) in negative-sense RNA viruses leads to defective genomes and triggers host interferon responses, making NP a key antiviral target.

bioRxiv · Mar 12, 2020 · PreprintMicrobiology

Engineering an RNA-based tissue-specific platform for genetic editing through use of a miRNA-enabled Cas12a

R. Moeller, K. Oishi, B. tenOever

This paper develops an RNA-based CRISPR-Cas12a system that enables tissue-specific genetic editing with reduced immunogenicity through miRNA-dependent crRNA maturation and self-inactivation.

bioRxiv · Mar 4, 2020 · PreprintBioengineering