Author

K. K. Chahal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

I. Kufareva· 2 shared A. M. Finch· 1 shared B. P. Wilkins· 1 shared C. C. Chen· 1 shared D. D. Durden· 1 shared J. L. J. Coleman· 1 shared J. Li· 1 shared M. Parle· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

I. Kufareva

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2 papers

Recent·Most cited

Orphan G protein-coupled receptor, GPR37L1: pharmacological toolbox empty once again

T. Ngo, B. P. Wilkins, S. S. So, P. Keov, K. K. Chahal, A. M. Finch, J. L. J. Coleman, I. Kufareva, N. J. Smith

The paper corrects a cloning error in a 2017 study on GPR37L1 ligand discovery and reports unsuccessful re-testing of predicted ligands, leading to a retraction initiative.

bioRxiv · Sep 11, 2020 · PreprintPharmacology & Toxicology

Nilotinib, an approved leukemia drug, inhibits Smoothened signaling in Hedgehog-dependent medulloblastoma

K. K. Chahal, J. Li, I. Kufareva, M. Parle, D. D. Durden, R. Wechsler-Reya, C. C. Chen, R. Abagyan

The paper shows Nilotinib inhibits Hedgehog signaling in medulloblastoma by directly targeting Smoothened, outperforming Vismodegib in cell lines and xenograft models.

bioRxiv · Mar 25, 2019Cancer Biology