Author

K. K. Khoo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

I. Galleano· 2 shared S. A. Pless· 2 shared D. Sarkar· 1 shared G. J. v. d. H. van Noort· 1 shared G. R. Uzun· 1 shared H. Harms· 1 shared J. S. Harrison· 1 shared K. Choudhury· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

I. Galleano

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Author profile →

2 papers

Recent·Most cited

Protein semisynthesis underscores role of a conserved lysine in activation and desensitization of acid-sensing ion channels

D. Sarkar, I. Galleano, S. A. Heusser, S. Y. Ou, G. R. Uzun, K. K. Khoo, G. J. v. d. H. van Noort, J. S. Harrison, S. A. Pless

This study uses semisynthesis to investigate the role of a conserved lysine in ASIC1a function, showing its importance in activation and desensitization.

bioRxiv · Jan 23, 2023Biophysics

Functional crosstalk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5

I. Galleano, H. Harms, K. Choudhury, K. K. Khoo, L. Delemotte, S. A. Pless

This paper investigates how phosphorylation and disease-causing mutations interact in Nav1.5, showing that mutations can amplify phosphorylation's impact on channel function and drug sensitivity.

bioRxiv · Dec 11, 2020Biophysics