H. Harms

Framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN

The paper establishes a framework to assess NALCN variant pathogenicity using functional and computational methods, distinguishing benign from gain- and loss-of-function variants.

Functional redundancy secures resilience of chain elongation communities upon pH shifts in closed bioreactor ecosystems

The paper investigates how pH changes affect microbial chain elongation communities in bioreactors, finding functional redundancy allows recovery of fermentation functions despite shifts in community composition.

Impact of fungal hyphae on growth and dispersal of obligate anaerobic bacteria in aerated habitats

The paper shows fungal hyphae create anoxic niches that allow obligate anaerobic bacteria to grow and disperse in aerated environments.

Phage co-transport with hyphal-riding bacteria fuels bacterial invasion in water-unsaturated microbial ecosystems

The paper shows hyphal-riding bacteria transport phages to new habitats, enhancing their colonization success in water-unsaturated environments.

Functional crosstalk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5

This paper investigates how phosphorylation and disease-causing mutations interact in Nav1.5, showing that mutations can amplify phosphorylation's impact on channel function and drug sensitivity.

Microbial resource management for ex situ biomethanation of hydrogen at alkaline pH

This study investigates microbial competition in ex situ biomethanation by adjusting media composition and stirring intensity to enhance CH4 production from H2/CO2.

Resilience trinity: safeguarding ecosystem services across three different time horizons and decision contexts

The paper introduces a conceptual framework called resilience trinity to manage ecosystem resilience across three decision contexts and time horizons.