Author

J. S. Harrison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Suzuki· 1 shared A. Varsani· 1 shared B. B. Larsen· 1 shared B. Strahl· 1 shared C. J. Petell· 1 shared C. Richet· 1 shared D. Bolhuis· 1 shared D. Sandoval· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCell Biology

A. Suzuki

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Protein semisynthesis underscores role of a conserved lysine in activation and desensitization of acid-sensing ion channels

D. Sarkar, I. Galleano, S. A. Heusser, S. Y. Ou, G. R. Uzun, K. K. Khoo, G. J. v. d. H. van Noort, J. S. Harrison, S. A. Pless

This study uses semisynthesis to investigate the role of a conserved lysine in ASIC1a function, showing its importance in activation and desensitization.

bioRxiv · Jan 23, 2023Biophysics

Co-evolutionary analysis suggests a role for TLR9 in papillomavirus restriction

K. M. King, B. B. Larsen, S. Gryseels, C. Richet, S. Kraberger, R. Jackson, M. Worobey, J. S. Harrison, A. Varsani, K. Van Doorslaer

This study identifies TLR9 as a pattern recognition receptor involved in detecting papillomaviruses and shows co-evolution between papillomaviruses and their hosts.

bioRxiv · Apr 17, 2021 · PreprintMicrobiology

Mechanically Transduced Immunosorbent Assay To Measure Protein-Protein Interactions

C. J. Petell, K. Randene, M. Pappas, D. Sandoval, B. Strahl, J. S. Harrison, J. P. Steimel

The paper introduces a novel mechanical assay to measure protein-protein interactions with high sensitivity and low reagent requirements, providing insights into previously inaccessible PPIs.

bioRxiv · Feb 5, 2021Biochemistry

In silico APC/C substrate discovery reveals cell cycle degradation of chromatin regulators including UHRF1

J. Kernan, R. C. Martinez-Chacin, X. Wang, R. L. Tiedemann, T. Bonacci, R. Choudhury, D. Bolhuis, J. S. Damrauer, F. Yan, J. S. Harrison, M. B. Major, K. Hoadley, A. Suzuki, S. B. Rothbart, N. G. Brown, M. J. Emanuele

The paper predicts APC/C substrates in silico, identifies chromatin regulators as substrates, and shows their cell cycle-dependent degradation and impact on DNA methylation.

bioRxiv · Apr 9, 2020Cell Biology